MOCOS

MOCOS
Identifiers
Aliases	MOCOS, hMCS, MCS, MOS, molybdenum cofactor sulfurase
External IDs	OMIM: 613274; MGI: 1915841; HomoloGene: 9931; GeneCards: MOCOS; OMA:MOCOS - orthologs
Gene location (Human)
Chr.	Chromosome 18 (human)
End	36,272,157 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	24,834,632 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; right lobe of liver; ; palpebral conjunctiva; ; right adrenal gland; ; right adrenal cortex; ; jejunal mucosa; ; left adrenal gland; ; left adrenal cortex; ; buccal mucosa cell; ; duodenum;
	Top expressed in
	granulocyte; ; left lobe of liver; ; esophagus; ; primary oocyte; ; jejunum; ; gastrula; ; respiratory epithelium; ; olfactory system; ; olfactory epithelium; ; duodenum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; molybdenum ion binding; pyridoxal phosphate binding; protein binding; catalytic activity; Mo-molybdopterin cofactor sulfurase activity; molybdenum cofactor sulfurtransferase activity; lyase activity;
Cellular component	cytosol; cellular component;
Biological process	Mo-molybdopterin cofactor biosynthetic process; molybdopterin cofactor biosynthetic process; molybdopterin cofactor metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	55034
	68591
	ENSG00000075643
	ENSMUSG00000039616
	Q96EN8
	Q14CH1
	NM_017947
	NM_026779
	NP_060417
	NP_081055
	Wikidata
View/Edit Human	View/Edit Mouse

Molybdenum cofactor sulfurase is an enzyme that in humans is encoded by the MOCOS gene.

MOCOS sulfurates the molybdenum cofactor of xanthine dehydrogenase (XDH) and aldehyde oxidase (AOX1), which is required for their enzymatic activities.