Myelin oligodendrocyte glycoprotein

MOG
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1Q70
Identifiers
Aliases	MOG, BTN6, BTNL11, MOGIG2, NRCLP7, myelin oligodendrocyte glycoprotein
External IDs	OMIM: 159465; MGI: 97435; HomoloGene: 111009; GeneCards: MOG; OMA:MOG - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	29,672,372 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	37,334,290 bp
RNA expression pattern
	Top expressed in
	C1 segment; ; substantia nigra; ; hippocampus proper; ; putamen; ; primary visual cortex; ; temporal lobe; ; Amygdala; ; caudate nucleus; ; Brodmann area 9; ; corpus callosum;
	Top expressed in
	deep cerebellar nuclei; ; lumbar subsegment of spinal cord; ; lateral geniculate nucleus; ; globus pallidus; ; ventral tegmental area; ; pontine nuclei; ; medial geniculate nucleus; ; central gray substance of midbrain; ; nucleus of stria terminalis; ; dorsal tegmental nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	virus receptor activity; signaling receptor binding;
Cellular component	integral component of membrane; plasma membrane; membrane; external side of plasma membrane;
Biological process	central nervous system development; viral entry into host cell; cell adhesion; viral process; regulation of immune response; T cell receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	4340
	17441
ENSG00000234096; ENSG00000232641; ENSG00000137345; ENSG00000230885; ENSG00000236561;
	ENSG00000237834; ENSG00000204655; ENSG00000234623
	ENSMUSG00000076439
	Q16653
	Q61885
NM_001008228; NM_001008229; NM_001170418; NM_002433; NM_206809;
	NM_206810; NM_206811; NM_206812; NM_206813; NM_206814; NM_001363610
	NM_010814
NP_001008229; NP_001008230; NP_001163889; NP_002424; NP_996532;
	NP_996533; NP_996534; NP_996535; NP_996537; NP_001350539
	NP_034944
	Wikidata
View/Edit Human	View/Edit Mouse

Myelin oligodendrocyte glycoprotein (MOG) is a glycoprotein believed to be important in the myelination of nerves in the central nervous system (CNS). In humans this protein is encoded by the MOG gene. It is speculated to serve as a necessary "adhesion molecule" to provide structural integrity to the myelin sheath and is known to develop late on the oligodendrocyte.