Mitochondrial pyruvate carrier 1

MPC1
Identifiers
Aliases	MPC1, BRP44L, MPYCD, dJ68L15.3, CGI-129, mitochondrial pyruvate carrier 1, SLC54A1
External IDs	OMIM: 614738; MGI: 1915240; HomoloGene: 9384; GeneCards: MPC1; OMA:MPC1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	166,383,013 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	8,516,493 bp
RNA expression pattern
	Top expressed in
	right ventricle; ; left ventricle; ; right auricle of heart; ; apex of heart; ; C1 segment; ; right lobe of liver; ; muscle of thigh; ; human kidney; ; parotid gland; ; myocardium;
	Top expressed in
	proximal tubule; ; right kidney; ; quadriceps femoris muscle; ; white adipose tissue; ; muscle of thigh; ; muscle tissue; ; skeletal muscle tissue; ; human kidney; ; cerebellar cortex; ; heart;
	More reference expression data
	n/a
Gene ontology
Molecular function	pyruvate transmembrane transporter activity; molecular function;
Cellular component	integral component of membrane; mitochondrial inner membrane; membrane; mitochondrion; integral component of mitochondrial inner membrane; cellular component;
Biological process	mitochondrial acetyl-CoA biosynthetic process from pyruvate; mitochondrial pyruvate transmembrane transport; cellular response to leukemia inhibitory factor; biological process;
	Sources:Amigo / QuickGO
Orthologs
	51660
	55951
	ENSG00000060762
	ENSMUSG00000023861
	Q9Y5U8
	P63030
	NM_001270879; NM_016098
	NM_018819; NM_001364918; NM_001364919
NP_001257808; NP_057182; NP_001363494; NP_001363495; NP_001363496;
	NP_001363497; NP_001363498
	NP_061289; NP_001351847; NP_001351848
	Wikidata
View/Edit Human	View/Edit Mouse

Mitochondrial pyruvate carrier 1 (MPC1), also known as brain protein 44-like (BRP44L) and SLC54A1, is a protein that in humans is encoded by the MPC1 gene. It is part of the Mitochondrial Pyruvate Carrier (MPC) protein family. This protein is involved in transport of pyruvate across the inner membrane of mitochondria in preparation for the pyruvate dehydrogenase reaction.