MPTP

MPTP
Names
	Preferred IUPAC name 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Identifiers
CAS Number	28289-54-5 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:17963 ;
ChEMBL	ChEMBL24172 ;
ChemSpider	1346 ;
ECHA InfoCard	100.044.475
EC Number	248-939-7;
IUPHAR/BPS	280;
KEGG	C04599 ;
MeSH	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
PubChem CID	1388;
UNII	9P21XSP91P ;
CompTox Dashboard (EPA)	DTXSID8040933 ;
	InChI InChI=1S/C12H15N/c1-13-9-7-12(8-10-13)11-5-3-2-4-6-11/h2-7H,8-10H2,1H3 Key: PLRACCBDVIHHLZ-UHFFFAOYSA-N ; InChI=1/C12H15N/c1-13-9-7-12(8-10-13)11-5-3-2-4-6-11/h2-7H,8-10H2,1H3 Key: PLRACCBDVIHHLZ-UHFFFAOYAV;
	SMILES c2ccccc2/C1=C/CN(C)CC1;
Properties
Chemical formula	C12H15N
Molar mass	173.259 g·mol−1
Melting point	40 °C (104 °F; 313 K)
Boiling point	128 to 132 °C (262 to 270 °F; 401 to 405 K) 12 Torr
Solubility in water	Slightly soluble
Hazards
NFPA 704 (fire diamond)	4 0 0
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is an organic compound. It is classified as a tetrahydropyridine. It is of interest as a precursor to the monoaminergic neurotoxin MPP⁺, which causes permanent symptoms of Parkinson's disease by destroying dopaminergic neurons in the substantia nigra of the brain. It has been used to study disease models in various animals.

While MPTP itself has no psychoactive effects, the compound may be accidentally produced during the manufacture of MPPP, a synthetic opioid drug with effects similar to those of morphine and pethidine (meperidine). The Parkinson-inducing effects of MPTP were first discovered following accidental injection as a result of contaminated MPPP.