MRAS

MRAS
Identifiers
Aliases	MRAS, M-RAs, R-RAS3, RRAS3, muscle RAS oncogene homolog, NS11
External IDs	OMIM: 608435; MGI: 1100856; HomoloGene: 7424; GeneCards: MRAS; OMA:MRAS - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	138,405,534 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	99,319,434 bp
RNA expression pattern
	Top expressed in
	external globus pallidus; ; internal globus pallidus; ; nucleus accumbens; ; right auricle of heart; ; tibial nerve; ; left ventricle; ; trigeminal ganglion; ; right frontal lobe; ; pars reticulata; ; middle temporal gyrus;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; subiculum; ; superior frontal gyrus; ; primary visual cortex; ; olfactory tubercle; ; neural layer of retina; ; genital tubercle; ; yolk sac; ; primary motor cortex; ; globus pallidus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; GTP-dependent protein binding; GTP binding; protein binding; GTPase activity; GDP binding;
Cellular component	plasma membrane; membrane; intracellular anatomical structure;
Biological process	multicellular organism development; muscle organ development; Ras protein signal transduction; actin cytoskeleton organization; signal transduction; cellular response to leukemia inhibitory factor;
	Sources:Amigo / QuickGO
Orthologs
	22808
	17532
	ENSG00000158186
	ENSMUSG00000032470
	O14807
	O08989
NM_001085049; NM_001252090; NM_001252091; NM_001252092; NM_001252093;
	NM_012219
	NM_008624
NP_001078518; NP_001239019; NP_001239020; NP_001239021; NP_001239022;
	NP_036351
	NP_032650
	Wikidata
View/Edit Human	View/Edit Mouse

Ras-related protein M-Ras, also known as muscle RAS oncogene homolog and R-Ras3, is a protein that in humans is encoded by the MRAS gene on chromosome 3. It is ubiquitously expressed in many tissues and cell types. This protein functions as a signal transducer for a wide variety of signaling pathways, including those promoting neural and bone formation as well as tumor growth. The MRAS gene also contains one of 27 SNPs associated with increased risk of coronary artery disease.