MYF6

MYF6
Identifiers
Aliases	MYF6, CNM3, MRF4, bHLHc4, myf-6, Myf6, myogenic factor 6
External IDs	OMIM: 159991; MGI: 97253; HomoloGene: 1850; GeneCards: MYF6; OMA:MYF6 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	80,709,474 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	107,330,598 bp
RNA expression pattern
	Top expressed in
	glutes; ; Skeletal muscle tissue of rectus abdominis; ; triceps brachii muscle; ; gastrocnemius muscle; ; biceps brachii; ; muscle of thigh; ; deltoid muscle; ; thoracic diaphragm; ; Skeletal muscle tissue of biceps brachii; ; quadriceps femoris muscle;
	Top expressed in
	muscle of thigh; ; temporal muscle; ; medial head of gastrocnemius muscle; ; sternocleidomastoid muscle; ; triceps brachii muscle; ; digastric muscle; ; intercostal muscle; ; soleus muscle; ; extraocular muscle; ; quadriceps femoris muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; protein dimerization activity; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; E-box binding; protein heterodimerization activity; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleoplasm; RNA polymerase II transcription regulator complex; nucleus;
Biological process	somitogenesis; cell differentiation; regulation of transcription, DNA-templated; positive regulation of muscle cell differentiation; regulation of transcription by RNA polymerase II; muscle cell fate commitment; muscle organ development; transcription by RNA polymerase II; positive regulation of skeletal muscle fiber development; multicellular organism development; positive regulation of transcription, DNA-templated; positive regulation of myoblast fusion; skeletal muscle tissue regeneration; positive regulation of myoblast differentiation; muscle tissue morphogenesis; skeletal muscle cell differentiation; negative regulation of transcription, DNA-templated; skeletal muscle tissue development; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	4618
	17878
	ENSG00000111046
	ENSMUSG00000035923
	P23409
	P15375
	NM_002469
	NM_008657
	NP_002460
	NP_032683
	Wikidata
View/Edit Human	View/Edit Mouse

Myogenic factor 6 (also known as Mrf4 or herculin) is a protein that in humans is encoded by the MYF6 gene. This gene is also known in the biomedical literature as MRF4 and herculin. MYF6 is a myogenic regulatory factor (MRF) involved in the process known as myogenesis.