Mitochondrial ribosomal protein L32

MRPL32
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMRPL32, L32mt, MRP-L32, bMRP-59b, HSPC283, mitochondrial ribosomal protein L32
External IDsOMIM: 611839; MGI: 2137226; HomoloGene: 32711; GeneCards: MRPL32; OMA:MRPL32 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

64983

75398

Ensembl

ENSG00000106591

ENSMUSG00000015672

UniProt

Q9BYC8

Q9DCI9

RefSeq (mRNA)

NM_031903

NM_029271

RefSeq (protein)

NP_114109

NP_083547

Location (UCSC)Chr 7: 42.93 – 42.95 MbChr 13: 14.78 – 14.79 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

39S ribosomal protein L32, mitochondrial is a protein that in humans is encoded by the MRPL32 gene.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L32 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome Xp.