Mitochondrial ribosomal protein L41

MRPL41
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3J7Y, 3J9M
Identifiers
Aliases	MRPL41, BMRP, MRP-L27, MRPL27, RPML27, PIG3, Mitochondrial ribosomal protein L41
External IDs	OMIM: 611846; MGI: 1333816; HomoloGene: 13036; GeneCards: MRPL41; OMA:MRPL41 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	137,552,555 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	24,865,110 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; myocardium of left ventricle; ; right auricle of heart; ; right ventricle; ; mucosa of transverse colon; ; cingulate gyrus; ; anterior cingulate cortex; ; caudate nucleus; ; putamen; ; muscle of thigh;
	Top expressed in
	facial motor nucleus; ; fossa; ; condyle; ; motor neuron; ; epithelium of lens; ; endocardial cushion; ; external carotid artery; ; internal carotid artery; ; renal corpuscle; ; atrioventricular junction;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	structural constituent of ribosome; protein binding; RNA binding;
Cellular component	mitochondrial inner membrane; ribosome; mitochondrion; mitochondrial large ribosomal subunit; ribonucleoprotein complex;
Biological process	cell cycle; mitochondrial translational elongation; mitochondrial translational termination; protein biosynthesis; apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	64975
	107733
	ENSG00000182154
	ENSMUSG00000036850
	Q8IXM3
	Q9CQN7
	NM_032477
	NM_001031808
	NP_115866
	NP_001026978
	Wikidata
View/Edit Human	View/Edit Mouse

39S ribosomal protein L41, mitochondrial is a protein that in humans is encoded by the MRPL41 gene.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the YmL27 ribosomal protein family.