MRPS24

MRPS24
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3J9M
Identifiers
Aliases	MRPS24, MRP-S24, S24mt, bMRP-47, bMRP47, HSPC335, mitochondrial ribosomal protein S24
External IDs	OMIM: 611986; MGI: 1928142; HomoloGene: 57043; GeneCards: MRPS24; OMA:MRPS24 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	43,869,893 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	5,665,680 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; muscle of thigh; ; apex of heart; ; left ventricle; ; right adrenal gland; ; body of pancreas; ; left adrenal cortex; ; right adrenal cortex; ; right auricle of heart; ; mucosa of transverse colon;
	Top expressed in
	endocardial cushion; ; lacrimal gland; ; medullary collecting duct; ; renal corpuscle; ; atrioventricular valve; ; facial motor nucleus; ; intercostal muscle; ; Paneth cell; ; epithelium of stomach; ; internal carotid artery;
	More reference expression data
	n/a
Gene ontology
Molecular function	structural constituent of ribosome; RNA binding;
Cellular component	mitochondrial inner membrane; ribosome; mitochondrial ribosome; mitochondrion; mitochondrial small ribosomal subunit;
Biological process	mitochondrial translational elongation; mitochondrial translational termination; protein biosynthesis; mitochondrial translation; biological process;
	Sources:Amigo / QuickGO
Orthologs
	64951
	64660
	ENSG00000062582
	ENSMUSG00000020477
	Q96EL2
	Q9CQV5
	NM_032014
	NM_026080; NM_001362871
	NP_114403
	NP_080356; NP_001349800
	Wikidata
View/Edit Human	View/Edit Mouse

28S ribosomal protein S24, mitochondrial is a protein that in humans is encoded by the MRPS24 gene.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 11.