MRPS26

MRPS26
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3J9M
Identifiers
Aliases	MRPS26, C20orf193, GI008, MRP-S13, MRP-S26, MRPS13, NY-BR-87, RPMS13, dJ534B8.3, mitochondrial ribosomal protein S26
External IDs	OMIM: 611988; MGI: 1333830; HomoloGene: 12778; GeneCards: MRPS26; OMA:MRPS26 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	3,048,250 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	130,410,615 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; right lobe of liver; ; myocardium of left ventricle; ; Brodmann area 9; ; right adrenal gland; ; skin of arm; ; left adrenal gland; ; left adrenal cortex; ; mucosa of transverse colon; ; right adrenal cortex;
	Top expressed in
	supraoptic nucleus; ; hair follicle; ; yolk sac; ; proximal tubule; ; right kidney; ; fossa; ; renal corpuscle; ; condyle; ; facial motor nucleus; ; external carotid artery;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	RNA binding;
Cellular component	mitochondrial inner membrane; ribosome; mitochondrial small ribosomal subunit; nucleoplasm; mitochondrion;
Biological process	peptide biosynthetic process; mitochondrial translational elongation; mitochondrial translational termination;
	Sources:Amigo / QuickGO
Orthologs
	64949
	99045
	ENSG00000125901
	ENSMUSG00000037740
	Q9BYN8
	Q80ZS3
	NM_030811
	NM_207207
	NP_110438
	NP_997090
	Wikidata
View/Edit Human	View/Edit Mouse

28S ribosomal protein S26, mitochondrial is a protein that in humans is encoded by the MRPS26 gene.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. This gene lies adjacent to and downstream of the gonadotropin-releasing hormone precursor gene.