MTUS1

MTUS1
Identifiers
Aliases	MTUS1, ATBP, ATIP, ICIS, MP44, MTSG1, microtubule associated tumor suppressor 1, microtubule associated scaffold protein 1, ATIP3
External IDs	OMIM: 609589; MGI: 2142572; HomoloGene: 100292; GeneCards: MTUS1; OMA:MTUS1 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	17,801,094 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	41,586,763 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; inferior ganglion of vagus nerve; ; inferior olivary nucleus; ; body of pancreas; ; thoracic diaphragm; ; right ventricle; ; subthalamic nucleus; ; biceps brachii; ; C1 segment; ; Skeletal muscle tissue of biceps brachii;
	Top expressed in
	zygote; ; secondary oocyte; ; primary oocyte; ; granulocyte; ; interventricular septum; ; lobe of cerebellum; ; cerebellar vermis; ; myocardium of ventricle; ; aortic valve; ; knee joint;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	microtubule binding;
Cellular component	cytoplasm; plasma membrane; Golgi apparatus; spindle; microtubule; cytoskeleton; membrane; mitochondrion; nucleus; microtubule organizing center; extracellular space; nucleolus; microtubule cytoskeleton;
Biological process	regulation of macrophage chemotaxis;
	Sources:Amigo / QuickGO
Orthologs
	57509
	102103
	ENSG00000129422
	ENSMUSG00000045636
	Q9ULD2
	Q5HZI1
NM_001001924; NM_001001925; NM_001001927; NM_001001931; NM_001166393;
	NM_020749; NM_001330470; NM_001363057; NM_001363058; NM_001363059; NM_001363060; NM_001363061; NM_001363062
	NM_001005863; NM_001005864; NM_001005865; NM_001286413
NP_001001924; NP_001001925; NP_001001931; NP_001159865; NP_001317399;
	NP_065800; NP_001349986; NP_001349987; NP_001349988; NP_001349989; NP_001349990; NP_001349991
NP_001005863; NP_001005864; NP_001005865; NP_001273342; NP_001390875;
	NP_001390876; NP_001390879; NP_001390881; NP_001390883; NP_001390884; NP_001390885
	Wikidata
View/Edit Human	View/Edit Mouse

Mitochondrial tumor suppressor 1 (MTSG1) or Microtubule-Associated Scaffold Protein 1 (MTUS1) is a candidate tumor suppressor protein encoded by the MTUS1 gene in humans. Expression levels of MTUS1 was reported to be lost in various types of human malignancies such as colon, ovarian, head-and-neck, pancreas, breast cancers, bladder, gastric, and lung cancers.