MYH14

MYH14
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5JLH
Identifiers
Aliases	MYH14, DFNA4, DFNA4A, MHC16, MYH17, NMHC II-C, NMHC-II-C, PNMHH, myosin, FP17425, myosin, heavy chain 14, non-muscle, myosin heavy chain 14
External IDs	OMIM: 608568; MGI: 1919210; HomoloGene: 23480; GeneCards: MYH14; OMA:MYH14 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	50,310,542 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	44,320,267 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; mucosa of ileum; ; gastrocnemius muscle; ; skin of leg; ; skin of abdomen; ; apex of heart; ; muscle of thigh; ; olfactory zone of nasal mucosa; ; minor salivary glands; ; tibialis anterior muscle;
	Top expressed in
	corneal stroma; ; saccule; ; superior surface of tongue; ; left colon; ; duodenum; ; right lung; ; gallbladder; ; right lung lobe; ; crypt of lieberkuhn of small intestine; ; ileum;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; calmodulin binding; actin filament binding; microfilament motor activity; actin binding; cytoskeletal motor activity; ATP binding; ATPase activity; microtubule motor activity; microtubule binding;
Cellular component	cytoplasm; cytosol; myosin II filament; membrane; growth cone; myelin sheath; stress fiber; axon; brush border; myosin II complex; actomyosin; extracellular exosome; myosin complex;
Biological process	skeletal muscle contraction; actomyosin structure organization; hearing; actin filament-based movement; vocalization behavior; regulation of cell shape; mitochondrion morphogenesis; skeletal muscle tissue development; neuronal action potential; microtubule-based movement;
	Sources:Amigo / QuickGO
Orthologs
	79784
	71960
	ENSG00000105357
	ENSMUSG00000030739
	Q7Z406
	Q6URW6
	NM_001077186; NM_001145809; NM_024729
	NM_001271538; NM_001271540; NM_028021
	NP_001070654; NP_001139281; NP_079005
	NP_001258467; NP_001258469; NP_082297
	Wikidata
View/Edit Human	View/Edit Mouse

Myosin-14 is a protein that in humans is encoded by the MYH14 gene.

This gene encodes a member of the myosin superfamily. Myosins are actin-dependent motor proteins with diverse functions, including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene.