MYO18B

MYO18B
Identifiers
Aliases	MYO18B, KFS4, myosin XVIIIB
External IDs	OMIM: 607295; MGI: 1921626; HomoloGene: 53435; GeneCards: MYO18B; OMA:MYO18B - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	26,031,045 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	113,044,228 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; gastrocnemius muscle; ; muscle of thigh; ; Skeletal muscle tissue of rectus abdominis; ; left ventricle; ; Skeletal muscle tissue of biceps brachii; ; right auricle of heart; ; quadriceps femoris muscle; ; vastus lateralis muscle; ; right ventricle;
	Top expressed in
	muscle of thigh; ; esophagus; ; spermatid; ; lip; ; skeletal muscle tissue; ; lens; ; embryo; ; quadriceps femoris muscle; ; superior frontal gyrus; ; heart;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; actin binding; cytoskeletal motor activity; ATP binding; microtubule motor activity; microtubule binding;
Cellular component	cytoplasm; unconventional myosin complex; sarcomere; nucleus; myosin complex; Z discdkac; filamentous actin;
Biological process	microtubule-based movement; vasculogenesis; in utero embryonic development;
	Sources:Amigo / QuickGO
Orthologs
	84700
	74376
	ENSG00000133454
	ENSMUSG00000072720
	Q8IUG5
	n/a
	NM_032608; NM_001318245
	NM_028901
	NP_001305174; NP_115997
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Myosin-XVIIIb is a protein that in humans is encoded by the MYO18B gene.

The protein encoded by this gene may regulate muscle-specific genes when in the nucleus and may influence intracellular trafficking when in the cytoplasm. The encoded protein functions as a homodimer and may interact with F actin. Mutations in this gene are associated with lung cancer.