Makkikha II
| Mar Makkikha II | |
|---|---|
| Patriarch of All the East | |
| Church | Church of the East | 
| See | Seleucia-Ctesiphon | 
| Installed | 1257 | 
| Term ended | 1265 | 
| Predecessor | Sabrisho V | 
| Successor | Denha I | 
| Other post(s) | Metropolitan of Nisibis | 
| Personal details | |
| Born | 13th century | 
| Died | 1265 | 
| Residence | Caliphal Palace, Baghdad | 
Makkikha II (also written Makika II) was Patriarch of the Church of the East from 1257 until his death in 1265. He succeeded the patriarch Sabrisho V ibn al-Masihi and was followed by Denha I.