Marginal zone

Marginal zone
Identifiers
FMA15852
Anatomical terminology

The marginal zone is the region at the interface between the non-lymphoid red pulp and the lymphoid white-pulp of the spleen. (Some sources consider it to be the part of red pulp which borders on the white pulp, while other sources consider it to be neither red pulp nor white pulp.)

A marginal zone also exists in the lymphoid follicles of lymph nodes. Those marginal zones contain naive B cells and memory B cells. In contrast to the marginal zone of the spleen, they are not characterized by containing additional non-recirculating B2 cells.

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