Methylphenobarbital

Methylphenobarbital
Clinical data
Trade names	Mebaral, generics
AHFS/Drugs.com	International Drug Names
MedlinePlus	a605022
Routes of; administration	By mouth (tablets)
ATC code	N03AA01 (WHO) ;
Legal status
Legal status	BR: Class B1 (Psychoactive drugs); CA: Schedule IV; DE: Prescription only (Anlage III for higher doses); UK: Class B; US: Schedule IV;
Pharmacokinetic data
Protein binding	70–76%
Metabolism	Liver
Elimination half-life	34 hours
Identifiers
	IUPAC name 5-Phenyl-5-ethyl-1-methylbarbituric acid;
CAS Number	115-38-8 ;
PubChem CID	8271;
DrugBank	DB00849 ;
ChemSpider	7972 ;
UNII	5NC67NU76B;
KEGG	D00700 ;
ChEBI	CHEBI:6758 ;
ChEMBL	ChEMBL45029 ;
CompTox Dashboard (EPA)	DTXSID4023258 ;
ECHA InfoCard	100.003.714
Chemical and physical data
Formula	C13H14N2O3
Molar mass	246.266 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C1N(C(=O)NC(=O)C1(c2ccccc2)CC)C;
	InChI InChI=1S/C13H14N2O3/c1-3-13(9-7-5-4-6-8-9)10(16)14-12(18)15(2)11(13)17/h4-8H,3H2,1-2H3,(H,14,16,18) ; Key:ALARQZQTBTVLJV-UHFFFAOYSA-N ;
	(verify)

Methylphenobarbital (INN), also known as mephobarbital (USAN, JAN) and mephobarbitone (BAN), marketed under brand names such as Mebaral, Mephyltaletten, Phemiton, and Prominal, is a drug which is a barbiturate derivative and is used primarily as an anticonvulsant, but also as a sedative and anxiolytic. It is the N-methylated analogue of phenobarbital and has similar indications, therapeutic value, and tolerability.