Mebfap

Mebfap
Clinical data
Other names	MEBFAP; 1-(5-Methoxybenzofuran-3-yl)-2-aminopropane; 5-Methoxy-3-(2-aminopropyl)benzofuran; 5-MeO-3-APB; 3-(2-Aminopropyl)-5-methoxybenzofuran
Drug class	Serotonin receptor modulator
Identifiers
	IUPAC name 1-(5-methoxy-1-benzofuran-3-yl)propan-2-amine;
CAS Number	140853-59-4;
PubChem CID	3025750;
ChemSpider	2291437;
ChEMBL	ChEMBL304628;
Chemical and physical data
Formula	C12H15NO2
Molar mass	205.257 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(CC1=COC2=C1C=C(C=C2)OC)N;
	InChI InChI=1S/C12H15NO2/c1-8(13)5-9-7-15-12-4-3-10(14-2)6-11(9)12/h3-4,6-8H,5,13H2,1-2H3; Key:PMAFEFSQHHKAKM-UHFFFAOYSA-N;

Mebfap, also known as 1-(5-methoxybenzofuran-3-yl)-2-aminopropane, is a serotonin receptor modulator of the benzofuran family. It is an analogue of 5-MeO-AMT in which the indole ring has been replaced with a benzofuran ring. Put another way, it is the analogue of 5-MeO-AMT in which the nitrogen atom in its indole ring has been replaced with a carbon atom to make a benzofuran ring. The drug is a ligand of serotonin receptors similarly to 5-MeO-AMT, but shows about one-sixth the affinity of 5-MeO-AMT. Mebfap was first described in the scientific literature by 1992.