Mefenamic acid

Mefenamic acid
Clinical data
Trade names	Ponstel, Ponstan, others
AHFS/Drugs.com	Monograph
MedlinePlus	a681028
Pregnancy; category	AU: C;
Routes of; administration	By mouth, rectal
ATC code	M01AG01 (WHO) ;
Legal status
Legal status	AU: S2 (Pharmacy medicine); CA: ℞-only; UK: POM (Prescription only); US: ℞-only;
Pharmacokinetic data
Bioavailability	90%
Protein binding	>90%
Metabolism	Liver (CYP2C9)
Elimination half-life	2 hours
Excretion	Kidney (52–67%), faeces (20–25%)
Identifiers
	IUPAC name 2-(2,3-dimethylphenyl)aminobenzoic acid;
CAS Number	61-68-7 ;
PubChem CID	4044;
IUPHAR/BPS	2593;
DrugBank	DB00784 ;
ChemSpider	3904 ;
UNII	367589PJ2C;
KEGG	D00151 ;
ChEBI	CHEBI:6717 ;
ChEMBL	ChEMBL686 ;
CompTox Dashboard (EPA)	DTXSID5023243 ;
ECHA InfoCard	100.000.467
Chemical and physical data
Formula	C15H15NO2
Molar mass	241.290 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(O)c2c(Nc1cccc(c1C)C)cccc2;
	InChI InChI=1S/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/h3-9,16H,1-2H3,(H,17,18) ; Key:HYYBABOKPJLUIN-UHFFFAOYSA-N ;
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Mefenamic acid is a member of the anthranilic acid derivatives (or fenamate) class of nonsteroidal anti-inflammatory drugs (NSAIDs), and is used to treat mild to moderate pain.

Its name derives from its systematic name, dimethylphenylaminobenzoic acid. It was discovered and brought to market by Parke-Davis as Ponstel in the 1960s. It became generic in the 1980s and is available worldwide under many brand names such as Meftal.