Melanosis coli

Melanosis coli
Other namesPseudomelanosis coli,
Melanosis coli identified on colonoscopy as a brownish moiré pattern on the wall of the colon

Melanosis coli, also pseudomelanosis coli, is a disorder of pigmentation of the wall of the colon, often identified at the time of colonoscopy. It is benign and may have no significant correlation with disease. The brown pigment is lipofuscin in macrophages, not melanin. It is most commonly associated with the use of certain laxatives.