Melperone

Melperone
Clinical data
Trade names	Buronil
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral, intramuscular injection
ATC code	N05AD03 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Pharmacokinetic data
Bioavailability	87% (IM), 54% (Oral via syrup), 65% (Oral, tablet)
Protein binding	50%
Metabolism	Hepatic
Elimination half-life	3–4 hours (oral); 6 hours (IM)
Excretion	Renal (70% as metabolites, 5.5–10.4% as unchanged drug)
Identifiers
	IUPAC name 1-(4-fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-one;
CAS Number	3575-80-2 ;
PubChem CID	15387;
DrugBank	DB09224 ;
ChemSpider	14646 ;
UNII	J8WA3K39B7;
KEGG	D07309 ;
ChEMBL	ChEMBL1531134;
CompTox Dashboard (EPA)	DTXSID0023298 ;
ECHA InfoCard	100.107.027
Chemical and physical data
Formula	C16H22FNO
Molar mass	263.356 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Fc1ccc(cc1)C(=O)CCCN2CCC(CC2)C;
	InChI InChI=1S/C16H22FNO/c1-13-8-11-18(12-9-13)10-2-3-16(19)14-4-6-15(17)7-5-14/h4-7,13H,2-3,8-12H2,1H3 ; Key:DKMFBWQBDIGMHM-UHFFFAOYSA-N ;
	(verify)

Melperone (Bunil (PT), Buronil (AT, BE, CZ, DK, FI^†, NL^†, NO^†, SE), Eunerpan (DE)) is an atypical antipsychotic of the butyrophenone chemical class, making it structurally related to the typical antipsychotic haloperidol. It first entered clinical use in 1960s.