Metitepine

Metitepine
Clinical data
Other names	Methiothepin; Methiothepine; Ro 8-6837 (maleate); VUFB-6276 (mesylate)
Identifiers
	IUPAC name 1-methyl-4-(8-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-6-yl)piperazine;
CAS Number	20229-30-5 ; 19728-88-2 (maleate);
PubChem CID	4106;
IUPHAR/BPS	89;
ChemSpider	3963;
UNII	55D94103HL;
ChEBI	CHEBI:64203;
CompTox Dashboard (EPA)	DTXSID2044000 ;
ECHA InfoCard	100.261.496
Chemical and physical data
Formula	C20H24N2S2
Molar mass	356.55 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN1CCN(CC1)C2Cc3ccccc3Sc4c2cc(cc4)SC;
	InChI InChI=1S/C20H24N2S2/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20/h3-8,14,18H,9-13H2,1-2H3; Key:RLJFTICUTYVZDG-UHFFFAOYSA-N;

Metitepine (INNTooltip International Nonproprietary Name; developmental code names Ro 8-6837 (maleate), VUFB-6276 (mesylate)), also known as methiothepin, is a drug described as a "psychotropic agent" of the tricyclic or tetracyclic group which was never marketed.

It acts as a non-selective antagonist of serotonin, dopamine, and adrenergic receptors, including of the serotonin 5-HT₁, 5-HT₂, 5-HT₅, 5-HT₆, and 5-HT₇ receptors. The drug has antipsychotic properties.