Mid-South Conference (MHSAA)
| Conference | MHSAA | 
|---|---|
| Commissioner | Lonnie Newland | 
| Sports fielded | 
 | 
| Division | (class) D | 
| No. of teams | 7 | 
| Headquarters | Marshall, Michigan | 
| Region | South/Central Michigan | 
| Locations | |
The Mid-South Conference (MSC) is an athletic conference affiliated with the MHSAA. All schools are Class D (small school). Members are located in Michigan.