Midwest Premier League
| Founded | 2019 | 
|---|---|
| First season | 2021 | 
| Country | United States | 
| Confederation | CONCACAF | 
| Divisions | 3 conferences & 6 divisions | 
| Number of clubs | 45 | 
| Domestic cup(s) | U.S. Open Cup (via qualifying tournament & NAC) National Amateur Cup (via USASA Region II) | 
| International cup(s) | CONCACAF Champions League (via U.S. Open Cup) | 
| Current champions | Cedars FC (Great Lakes East), Northern Indiana FC (Great Lakes West), Cedar Rapids Inferno (Gateway), RWB Adria Chicago (Heartland) (2024 season) | 
| Most championships | Milwaukee Bavarian SC Ajax St. Louis Inter Detroit (2 division titles) | 
| Website | midwestpl.com | 
| Current: 2025 MWPL season | |
The Midwest Premier League (MWPL) is an American amateur and semi-professional soccer league. The league spans primarily the eastern and central portions of the Midwestern United States.