Santa María Mixtequilla
| Santa María Mixtequilla | |
|---|---|
| Municipality and town | |
| Coordinates: 16°22′N 95°15′W / 16.367°N 95.250°W | |
| Country | Mexico | 
| State | Oaxaca | 
| Population  (2020) | |
|  • Total | 4,690 | 
| Time zone | UTC-6 (Central Standard Time) | 
| • Summer (DST) | UTC-5 (Central Daylight Time) | 
Santa María Mixtequilla is a town and municipality in Oaxaca in south-western Mexico. The municipality covers an area of km2. It is part of the Tehuantepec District in the west of the Istmo Region.
As of 2010, the municipality had a total population of 3,638.