Molise

Molise
Mulise (Neapolitan)
Moliš (Slavomolisano)
Coordinates: 41°41′59″N 14°36′40″E / 41.6997°N 14.6111°E / 41.6997; 14.6111
CountryItaly
CapitalCampobasso
Government
  PresidentFrancesco Roberti (FI)
Area
  Total
4,460.65 km2 (1,722.27 sq mi)
Population
 (2025)
  Total
287,966
  Density65/km2 (170/sq mi)
Demonym(s)English: Molisan
Italian: Molisano (man)
Italian: Molisana (woman)
GDP
  Total€6.452 billion (2021)
Time zoneUTC+1 (CET)
  Summer (DST)UTC+2 (CEST)
ISO 3166 codeIT-67
HDI (2021)0.874
very high · 15th of 21
NUTS RegionITF
Websitewww.regione.molise.it

Molise (UK: /mɒˈlz/ mol-EE-zay, US: /ˈmliz, mˈlz/ MOH-lee-zay, moh-LEE-zay; Italian: [moˈliːze]; Molisan: Mulise, pronounced [mə'li.zə]) is a region in Southern Italy. Until 1963, it formed part of the region of Abruzzi e Molise together with Abruzzo. The split, which did not become effective until 1970, makes Molise the newest region in Italy. Covering 4,460.65 square kilometres (1,722 sq mi), it is the second smallest region in the country, after the Aosta Valley, and has a population of 287,966 as of 2025.

The region is split into two provinces, named after their capitals: Campobasso and Isernia. Campobasso also serves as the regional capital.