Mosopelea
| Total population | |
|---|---|
| No longer a distinct tribe, merged into the Tunica-Biloxi | |
| Regions with significant populations | |
| United States (formerly Ohio, Louisiana) | |
| Languages | |
| Ofo, English, French | |
| Religion | |
| Native tribal religion | |
| Related ethnic groups | |
| Biloxi, Tunica |
The Mosopelea or Ofo (also Ofogoula) were a Siouan-speaking Native American people who historically lived near the upper Ohio River. In reaction to Iroquois Confederacy invasions to take control of hunting grounds in the late 17th century, they moved south to the lower Mississippi River. They finally settled in central Louisiana, where they assimilated with the Tunica and the Siouan-speaking Biloxi. They spoke the Ofo language, generally classified as a Siouan language.