Moxestrol

Moxestrol
Clinical data
Trade names	Surestryl
Other names	R-2858, RU-2858, NSC-118191; 11β-Methoxy-17α-ethynylestradiol; 11β-MeO-EE 11β-Methoxy-17α-ethynylestra-1,3,5(10)-triene-3,17β-diol
Pregnancy; category	X (Contraindicated);
Routes of; administration	By mouth
Drug class	Estrogen; Estrogen ether
ATC code	G03CB04 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Pharmacokinetic data
Bioavailability	33%
Protein binding	Minimal
Metabolism	Liver
Elimination half-life	8.2 hours
Identifiers
	IUPAC name (8S,9S,11S,13S,14S,17R)-17-ethynyl-11-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol;
CAS Number	34816-55-2;
PubChem CID	11954041;
ChemSpider	10128336;
UNII	6923NT44OW;
KEGG	C14757;
ChEBI	CHEBI:34857;
ChEMBL	ChEMBL1628161;
CompTox Dashboard (EPA)	DTXSID8022375 ;
Chemical and physical data
Formula	C21H26O3
Molar mass	326.436 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC12CC(C3C(C1CCC2(C#C)O)CCC4=C3C=CC(=C4)O)OC;
	InChI InChI=1S/C21H26O3/c1-4-21(23)10-9-17-16-7-5-13-11-14(22)6-8-15(13)19(16)18(24-3)12-20(17,21)2/h1,6,8,11,16-19,22-23H,5,7,9-10,12H2,2-3H3/t16-,17-,18-,19+,20-,21-/m0/s1; Key:MTMZZIPTQITGCY-OLGWUGKESA-N;

Moxestrol, sold under the brand name Surestryl, is an estrogen medication which has been used in Europe for the treatment of menopausal symptoms and menstrual disorders. It is taken by mouth. In addition to its use as a medication, moxestrol has been used in scientific research as a radioligand of the estrogen receptor.