MuSK protein
| muscle, skeletal, receptor tyrosine kinase | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | MUSK | ||||||
| NCBI gene | 4593 | ||||||
| HGNC | 7525 | ||||||
| OMIM | 601296 | ||||||
| RefSeq | NM_005592 | ||||||
| UniProt | O15146 | ||||||
| Other data | |||||||
| Locus | Chr. 9 q31.3-q32 | ||||||
| |||||||
MuSK (for Muscle-Specific Kinase) is a receptor tyrosine kinase required for the formation and maintenance of the neuromuscular junction. It is activated by a nerve-derived proteoglycan called agrin, which is similarly also required for neuromuscular junction formation.