Tolnaftate

Tolnaftate
Clinical data
Trade names	Tinactin
Other names	2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate
AHFS/Drugs.com	Monograph
MedlinePlus	a682617
ATC code	D01AE18 (WHO) ;
Legal status
Legal status	In general: Over-the-counter (OTC);
Identifiers
	IUPAC name O-2-Naphthyl methyl(3-methylphenyl)thiocarbamate;
CAS Number	2398-96-1 ;
PubChem CID	5510;
DrugBank	DB00525 ;
ChemSpider	5309 ;
UNII	06KB629TKV;
KEGG	D00381 ;
ChEBI	CHEBI:9620 ;
ChEMBL	ChEMBL83668 ;
CompTox Dashboard (EPA)	DTXSID3042477 ;
ECHA InfoCard	100.017.516
Chemical and physical data
Formula	C19H17NOS
Molar mass	307.41 g·mol−1
3D model (JSmol)	Interactive image;
Melting point	110 to 111.5 °C (230.0 to 232.7 °F)
	SMILES S=C(Oc2ccc1c(cccc1)c2)N(c3cc(ccc3)C)C;
	InChI InChI=1S/C19H17NOS/c1-14-6-5-9-17(12-14)20(2)19(22)21-18-11-10-15-7-3-4-8-16(15)13-18/h3-13H,1-2H3 ; Key:FUSNMLFNXJSCDI-UHFFFAOYSA-N ;
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Tolnaftate (INN), sold under the brand name TAGRID, among others, is a synthetic thiocarbamate used as an anti-fungal agent that may be sold without medical prescription in most jurisdictions. It is supplied as a cream, powder, spray, liquid, and liquid aerosol. Tolnaftate is used to treat fungal conditions such as jock itch, athlete's foot and ringworm. Tolnaftate was discovered by Teruhisa Noguchi in 1962 while he was working for the Nippon Soda Company.