N-Acetylaspartic acid

N-Acetylaspartic acid
Names
	IUPAC name 2-Acetamidobutanedioic acid
Identifiers
CAS Number	2545-40-6 ; 997-55-7 S ;
3D model (JSmol)	Interactive image;
Beilstein Reference	1726198 S
ChEBI	CHEBI:21547 ;
ChEMBL	ChEMBL1162493 ;
ChemSpider	88007 ; 677387 R ;
ECHA InfoCard	100.012.403
EC Number	219-827-5;
KEGG	C01042 ;
MeSH	N-acetylaspartate
PubChem CID	97508; 774916 R; 65065 S;
RTECS number	CI9098600;
UNII	445Y04YIWR ;
CompTox Dashboard (EPA)	DTXSID40897219 ;
	InChI InChI=1S/C6H9NO5/c1-3(8)7-4(6(11)12)2-5(9)10/h4H,2H2,1H3,(H,7,8)(H,9,10)(H,11,12) Key: OTCCIMWXFLJLIA-UHFFFAOYSA-N ;
	SMILES CC(=O)N[C@@H](CC(=O)O)C(=O)O;
Properties
Chemical formula	C6H9NO5
Molar mass	175.140 g·mol−1
Appearance	Colourless, transparent crystals
Melting point	137 to 140 °C (279 to 284 °F; 410 to 413 K)
Boiling point	141 to 144 °C (286 to 291 °F; 414 to 417 K)
log P	−2.209
Acidity (pKa)	3.142
Basicity (pKb)	10.855
Hazards
	GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H315, H319, H335
Precautionary statements	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
Related compounds
Related alkanoic acids	3-Ureidopropionic acid; beta-Ureidoisobutyric acid; Carbamoyl aspartic acid; Aceglutamide; N-Acetylglutamic acid; Citrulline;
Related compounds	Bromisoval; Carbromal;
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

N-Acetylaspartic acid, or N-acetylaspartate (NAA), is a derivative of aspartic acid with a formula of C₆H₉NO₅ and a molecular weight of 175.139.

NAA is the second-most-concentrated molecule in the brain after the amino acid glutamate. It is detected in the adult brain in neurons, oligodendrocytes and myelin and is synthesized in the mitochondria from the amino acid aspartic acid and acetyl-coenzyme A.