N-alpha-acetyltransferase 10

NAA10
Identifiers
Aliases	NAA10, ARD1, ARD1A, ARD1P, DXS707, MCOPS1, NATD, TE2, OGDNS, N(alpha)-acetyltransferase 10, NatA catalytic subunit, hARD1, N-alpha-acetyltransferase 10, NatA catalytic subunit
External IDs	OMIM: 300013; MGI: 1915255; HomoloGene: 2608; GeneCards: NAA10; OMA:NAA10 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	153,935,080 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	72,965,550 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; apex of heart; ; gastrocnemius muscle; ; left coronary artery; ; muscle of thigh; ; anterior pituitary; ; body of uterus; ; right frontal lobe; ; muscle layer of sigmoid colon; ; ascending aorta;
	Top expressed in
	epiblast; ; embryo; ; embryo; ; bone marrow; ; ventricular zone; ; lip; ; neural tube; ; autopod region; ; tail of embryo; ; hand;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ribosome binding; transferase activity; N-acetyltransferase activity; acetyltransferase activity; peptide-serine-N-acetyltransferase activity; acyltransferase activity; protein binding; peptide-glutamate-N-acetyltransferase activity; peptide alpha-N-acetyltransferase activity;
Cellular component	cytoplasm; NatA complex; cytosolic ribosome; nucleolus; intracellular anatomical structure; membrane; nucleus; cytosol;
Biological process	N-terminal peptidyl-glutamic acid acetylation; N-terminal peptidyl-serine acetylation; internal protein amino acid acetylation; N-terminal protein amino acid acetylation; protein acetylation; negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric;
	Sources:Amigo / QuickGO
Orthologs
	8260
	56292
	ENSG00000102030
	ENSMUSG00000031388
	P41227
	Q9QY36
	NM_003491; NM_001256119; NM_001256120
	NM_001177965; NM_019870; NM_001310538
	NP_001243048; NP_001243049; NP_003482
	NP_001171436; NP_001297467; NP_063923
	Wikidata
View/Edit Human	View/Edit Mouse

N-alpha-acetyltransferase 10 (NAA10) also known as NatA catalytic subunit Naa10 and arrest-defective protein 1 homolog A (ARD1A) is an enzyme subunit that in humans is encoded NAA10 gene. Together with its auxiliary subunit Naa15, Naa10 constitutes the NatA (N^α-acetyltransferase A) complex that specifically catalyzes the transfer of an acetyl group from acetyl-CoA to the N-terminal primary amino group of certain proteins. In higher eukaryotes, 5 other N-acetyltransferase (NAT) complexes, NatB-NatF, have been described that differ both in substrate specificity and subunit composition.