NAA60

NAA60
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5ICW, 5ICV
Identifiers
Aliases	NAA60, HAT4, NAT15, N(alpha)-acetyltransferase 60, NatF catalytic subunit, hNaa60, NatF, N-alpha-acetyltransferase 60, NatF catalytic subunit
External IDs	OMIM: 614246; MGI: 1922013; HomoloGene: 32610; GeneCards: NAA60; OMA:NAA60 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	3,486,953 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	3,722,634 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; endothelial cell; ; mucosa of ileum; ; parotid gland; ; body of stomach; ; mucosa of transverse colon; ; metanephric glomerulus; ; apex of heart; ; renal medulla; ; duodenum;
	Top expressed in
	ankle joint; ; granulocyte; ; perirhinal cortex; ; choroid plexus of fourth ventricle; ; entorhinal cortex; ; superior frontal gyrus; ; visual cortex; ; primary visual cortex; ; Ileal epithelium; ; tail of embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	histone acetyltransferase activity; transferase activity; H4 histone acetyltransferase activity; acyltransferase activity; peptide alpha-N-acetyltransferase activity; protein homodimerization activity; N-acetyltransferase activity;
Cellular component	Golgi membrane; Golgi apparatus; membrane;
Biological process	histone H4 acetylation; nucleosome assembly; cell population proliferation; N-terminal peptidyl-methionine acetylation; N-terminal protein amino acid acetylation; chromosome segregation; chromatin organization; histone H3 acetylation;
	Sources:Amigo / QuickGO
Orthologs
	79903
	74763
	ENSG00000122390
	ENSMUSG00000005982
	Q9H7X0
	Q9DBU2
NM_001083600; NM_001083601; NM_024845; NM_001317093; NM_001317094;
	NM_001317095; NM_001317096; NM_001317097; NM_001317098
	NM_001290689; NM_029090
NP_001077069; NP_001077070; NP_001304022; NP_001304023; NP_001304024;
	NP_001304025; NP_001304026; NP_001304027; NP_079121
	NP_001277618; NP_083366
	Wikidata
View/Edit Human	View/Edit Mouse

Nα-acetyltransferase 60 (NAA60) also known as NatF is a member of the N-terminal acetyltransferase (NAT) family of proteins. NATs bind to acetyl-coenzyme A (Ac-CoA) as well as to the protein N-terminus, and enzymatically transfer the acetyl group from Ac-CoA to the free backbone amino group (NH₃⁺) on the first residue of the protein. NATs are mono- or multisubunit enzymes consisting of one catalytic subunit and up to two auxiliary subunits, however, only a catalytic subunit of NAA60 has been identified so far.