NAV1

NAV1
Identifiers
Aliases	NAV1, POMFIL3, STEERIN1, UNC53H1, neuron navigator 1
External IDs	OMIM: 611628; MGI: 2183683; HomoloGene: 10719; GeneCards: NAV1; OMA:NAV1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	201,826,969 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	135,615,843 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; external globus pallidus; ; myocardium of left ventricle; ; lateral nuclear group of thalamus; ; saphenous vein; ; pars reticulata; ; Brodmann area 23; ; middle temporal gyrus; ; inferior ganglion of vagus nerve; ; pericardium;
	Top expressed in
	Rostral migratory stream; ; tail of embryo; ; internal carotid artery; ; genital tubercle; ; external carotid artery; ; ventromedial nucleus; ; vas deferens; ; subiculum; ; ganglionic eminence; ; anterior amygdaloid area;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; microtubule cytoskeleton; microtubule; cytoskeleton; axon initial segment;
Biological process	multicellular organism development; cell differentiation; neuron migration; microtubule bundle formation; nervous system development; neurogenesis;
	Sources:Amigo / QuickGO
Orthologs
	89796
	215690
	ENSG00000134369
	ENSMUSG00000009418
	Q8NEY1
	Q8CH77
	NM_001167738; NM_020443
	NM_173437
	NP_001161210; NP_065176
	NP_775613
	Wikidata
View/Edit Human	View/Edit Mouse

Neuron navigator 1 is a protein that in humans is encoded by the NAV1 gene.

This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known.