NCAPG2

NCAPG2
Identifiers
Aliases	NCAPG2, CAP-G2, CAPG2, LUZP5, MTB, hCAP-G2, non-SMC condensin II complex subunit G2, 3KS
External IDs	OMIM: 608532; MGI: 1923294; HomoloGene: 9820; GeneCards: NCAPG2; OMA:NCAPG2 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	158,704,804 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	116,427,351 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; secondary oocyte; ; sperm; ; ganglionic eminence; ; bone marrow; ; bone marrow cells; ; trabecular bone; ; stromal cell of endometrium; ; gonad; ; right testis;
	Top expressed in
	nasal epithelium; ; olfactory epithelium; ; secondary oocyte; ; primary oocyte; ; zygote; ; ventricular zone; ; fetal liver hematopoietic progenitor cell; ; tail of embryo; ; dermis; ; superior cervical ganglion;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	methylated histone binding; protein binding; bHLH transcription factor binding; molecular function regulator;
Cellular component	membrane; nucleus; nucleoplasm; condensin complex; nuclear speck;
Biological process	cell division; cell cycle; chromosome condensation; inner cell mass cell proliferation; transcription by RNA polymerase II; erythrocyte differentiation; negative regulation of erythrocyte differentiation; positive regulation of protein tyrosine kinase activity; positive regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	54892
	76044
	ENSG00000146918
	ENSMUSG00000042029
	Q86XI2
	Q6DFV1
	NM_001281932; NM_001281933; NM_017760
	NM_133762
	NP_001268861; NP_001268862; NP_060230
	NP_598523
	Wikidata
View/Edit Human	View/Edit Mouse

Condensin-2 complex subunit G2 (CAP-G2) also known as chromosome-associated protein G2 (CAP-G2) or leucine zipper protein 5 (LUZP5) is a protein that in humans is encoded by the NCAPG2 gene. CAP-G2 is a subunit of condensin II, a large protein complex involved in chromosome condensation. It interacts with PLK1 through its C-terminal region during mitosis