NCAPH

NCAPH
Identifiers
Aliases	NCAPH, BRRN1, CAP-H, non-SMC condensin I complex subunit H, MCPH23, CAPH
External IDs	OMIM: 602332; MGI: 2444777; HomoloGene: 133986; GeneCards: NCAPH; OMA:NCAPH - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	96,377,091 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	126,975,874 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; gonad; ; left testis; ; right testis; ; testicle; ; secondary oocyte; ; sperm; ; mucosa of transverse colon; ; rectum;
	Top expressed in
	otic placode; ; tail of embryo; ; saccule; ; genital tubercle; ; otic vesicle; ; fetal liver hematopoietic progenitor cell; ; vas deferens; ; condyle; ; fossa; ; medial ganglionic eminence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; chromatin binding; DNA topoisomerase binding; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity;
Cellular component	cytoplasm; membrane; chromosome; condensin complex; nucleus; cytosol;
Biological process	cell division; cell cycle; chromosome condensation; mitotic chromosome condensation; meiotic chromosome condensation; meiotic chromosome segregation; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity; female meiotic nuclear division; female meiosis chromosome separation;
	Sources:Amigo / QuickGO
Orthologs
	23397
	215387
	ENSG00000121152
	ENSMUSG00000034906
	Q15003
	Q8C156
	NM_001281710; NM_001281711; NM_001281712; NM_015341
	NM_144818
	NP_001268639; NP_001268640; NP_001268641; NP_056156
	NP_659067
	Wikidata
View/Edit Human	View/Edit Mouse

Condensin complex subunit 2 also known as chromosome-associated protein H (CAP-H) or non-SMC condensin I complex subunit H (NCAPH) is a protein that in humans is encoded by the NCAPH gene. CAP-H is a subunit of condensin I, a large protein complex involved in chromosome condensation. Abnormal expression of NCAPH may be linked to various types of carcinogenesis as a prognostic indicator.