NDFIP1

NDFIP1
Identifiers
Aliases	NDFIP1, N4WBP5, Nedd4 family interacting protein 1
External IDs	OMIM: 612050; MGI: 1929601; HomoloGene: 12730; GeneCards: NDFIP1; OMA:NDFIP1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	142,154,440 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	38,598,356 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; endothelial cell; ; Pons; ; middle temporal gyrus; ; superior frontal gyrus; ; entorhinal cortex; ; postcentral gyrus; ; lateral nuclear group of thalamus; ; spinal ganglia; ; primary visual cortex;
	Top expressed in
	cingulate gyrus; ; Epithelium of choroid plexus; ; medial dorsal nucleus; ; mammillary body; ; ventral tegmental area; ; dorsomedial hypothalamic nucleus; ; ventromedial nucleus; ; median eminence; ; seminal vesicula; ; paraventricular nucleus of hypothalamus;
	More reference expression data
	n/a
Gene ontology
Molecular function	signal transducer activity; protein binding; WW domain binding;
Cellular component	integral component of membrane; endosome; membrane; Golgi membrane; extracellular region; cell cortex; perinuclear region of cytoplasm; endosome membrane; cell junction; dendrite; cell projection; neuron projection; synapse; Golgi apparatus;
Biological process	regulation of myeloid leukocyte differentiation; regulation of isotype switching to IgG isotypes; positive regulation of protein catabolic process; negative regulation of interleukin-4 production; metal ion transport; negative regulation of isotype switching to IgE isotypes; negative regulation of gene expression; negative regulation of T cell proliferation; regulation of lymphocyte differentiation; negative regulation of protein transport; negative regulation of type 2 immune response; positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of protein ubiquitination; negative regulation of inflammatory response; negative regulation of transporter activity; vacuolar transport; cellular iron ion homeostasis; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	80762
	65113
	ENSG00000131507
	ENSMUSG00000024425
	Q9BT67
	Q8R0W6
	NM_030571
	NM_022996; NM_001355749
	NP_085048
	NP_075372; NP_001342678
	Wikidata
View/Edit Human	View/Edit Mouse

Nedd4 family interacting protein 1 is a protein that in humans is encoded by the NDFIP1 gene.