NDST1

NDST1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1NST
Identifiers
Aliases	NDST1, HSST, NST1, MRT46, N-deacetylase/N-sulfotransferase 1, N-deacetylase and N-sulfotransferase 1
External IDs	OMIM: 600853; MGI: 104719; HomoloGene: 20386; GeneCards: NDST1; OMA:NDST1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	150,558,211 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	60,881,722 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; C1 segment; ; olfactory bulb; ; subthalamic nucleus; ; inferior ganglion of vagus nerve; ; right lobe of liver; ; lateral nuclear group of thalamus; ; mucosa of esophagus; ; inferior olivary nucleus; ; upper lobe of left lung;
	Top expressed in
	right lung lobe; ; left lung; ; left lung lobe; ; lacrimal gland; ; epithelium of stomach; ; left lobe of liver; ; human fetus; ; salivary gland; ; vas deferens; ; digastric muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; sulfotransferase activity; deacetylase activity; catalytic activity; hydrolase activity; N-acetylglucosamine deacetylase activity; protein binding; [heparan sulfate-glucosamine N-sulfotransferase activity]; heparan sulfate N-acetylglucosaminyltransferase activity; heparan sulfate sulfotransferase activity;
Cellular component	integral component of membrane; Golgi apparatus; membrane; Golgi membrane;
Biological process	cardiac septum development; heparin biosynthetic process; embryonic neurocranium morphogenesis; coronary vasculature development; respiratory gaseous exchange by respiratory system; fibroblast growth factor receptor signaling pathway; aorta development; heart development; glycosaminoglycan biosynthetic process; animal organ morphogenesis; embryonic viscerocranium morphogenesis; polysaccharide biosynthetic process; forebrain development; metabolism; protein sulfation; inflammatory response; midbrain development; glycosaminoglycan metabolic process; heparan sulfate proteoglycan biosynthetic process; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; positive regulation of MAPK cascade; positive regulation of smoothened signaling pathway; sulfur compound metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	3340
	15531
	ENSG00000070614
	ENSMUSG00000054008
	P52848
	Q3UHN9
	NM_001301063; NM_001543
NM_008306; NM_001348100; NM_001348101; NM_001348102; NM_001348103;
	NM_001348146
	NP_001287992; NP_001534
NP_032332; NP_001335029; NP_001335030; NP_001335031; NP_001335032;
	NP_001335075
	Wikidata
View/Edit Human	View/Edit Mouse

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 is an enzyme. In humans, it is encoded by the NDST1 gene.