NDUFA11

NDUFA11
Identifiers
Aliases	NDUFA11, B14.7, CI-B14.7, NADH:ubiquinone oxidoreductase subunit A11, MC1DN14
External IDs	OMIM: 612638; MGI: 3645174; HomoloGene: 17926; GeneCards: NDUFA11; OMA:NDUFA11 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	5,904,006 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; cardiac muscle tissue of right atrium; ; myocardium of left ventricle; ; right auricle of heart; ; apex of heart; ; left adrenal cortex; ; skin of arm; ; right adrenal gland; ; right adrenal cortex; ; mucosa of ileum;
	n/a
	More reference expression data
	n/a
Orthologs
	126328
	239760
	ENSG00000174886
	n/a
	Q86Y39
	n/a
	NM_001193375; NM_175614
	n/a
	NP_001180304; NP_783313
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 is an enzyme that in humans is encoded by the NDUFA11 gene. The NDUFA11 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain Mutations in subunits of NADH dehydrogenase (ubiquinone), also known as Complex I, frequently lead to complex neurodegenerative diseases such as Leigh's syndrome. Mutations in this gene are associated with severe mitochondrial complex I deficiency.