NDUFA13

NDUFA13
Identifiers
Aliases	NDUFA13, B16.6, CDA016, GRIM-19, GRIM19, CGI-39, NADH:ubiquinone oxidoreductase subunit A13, MC1DN28
External IDs	OMIM: 609435; MGI: 1914434; HomoloGene: 41083; GeneCards: NDUFA13; OMA:NDUFA13 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	19,529,054 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	70,355,208 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; left ventricle; ; right auricle of heart; ; right testis; ; putamen; ; left testis; ; prefrontal cortex; ; caudate nucleus; ; nucleus accumbens; ; Brodmann area 9;
	Top expressed in
	interventricular septum; ; choroid plexus of fourth ventricle; ; right kidney; ; proximal tubule; ; gastrocnemius muscle; ; left ventricle; ; soleus muscle; ; quadriceps femoris muscle; ; thoracic diaphragm; ; tibialis anterior muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	NADH dehydrogenase (ubiquinone) activity; protein binding; ATP binding; NADH dehydrogenase activity;
Cellular component	cytoplasm; integral component of membrane; mitochondrial membranes; membrane; nucleoplasm; mitochondrion; mitochondrial respirasome; mitochondrial inner membrane; respirasome; nucleus; mitochondrial respiratory chain complex I;
Biological process	cellular response to retinoic acid; protein insertion into mitochondrial inner membrane; positive regulation of protein catabolic process; cellular response to interferon-beta; negative regulation of intrinsic apoptotic signaling pathway; reactive oxygen species metabolic process; positive regulation of peptidase activity; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of cell growth; apoptotic signaling pathway; negative regulation of transcription, DNA-templated; apoptotic process; extrinsic apoptotic signaling pathway; mitochondrial respiratory chain complex I assembly; mitochondrial electron transport, NADH to ubiquinone;
	Sources:Amigo / QuickGO
Orthologs
	51079
	67184
	ENSG00000186010
	ENSMUSG00000036199
	Q9P0J0
	Q9ERS2
	NM_015965
	NM_023312; NM_001382215
	NP_057049
	NP_075801.1; NP_075801
	Wikidata
View/Edit Human	View/Edit Mouse

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 is an enzyme that in humans is encoded by the NDUFA13 gene. The NDUFA13 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain.