NDUFA2

NDUFA2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1S3A
Identifiers
Aliases	NDUFA2, B8, CD14, CIB8, NADH:ubiquinone oxidoreductase subunit A2, MC1DN13
External IDs	OMIM: 602137; MGI: 1343103; HomoloGene: 37628; GeneCards: NDUFA2; OMA:NDUFA2 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	140,647,771 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	36,877,610 bp
RNA expression pattern
	Top expressed in
	biceps brachii; ; right ventricle; ; Skeletal muscle tissue of biceps brachii; ; apex of heart; ; triceps brachii muscle; ; mucosa of transverse colon; ; vastus lateralis muscle; ; thoracic diaphragm; ; left ventricle; ; body of tongue;
	Top expressed in
	aortic valve; ; fossa; ; facial motor nucleus; ; ascending aorta; ; medullary collecting duct; ; condyle; ; renal corpuscle; ; intercostal muscle; ; right kidney; ; Paneth cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	NADH dehydrogenase (ubiquinone) activity;
Cellular component	mitochondrial inner membrane; mitochondrial respiratory chain complex I; respirasome; membrane; mitochondrion; mitochondrial membranes;
Biological process	mitochondrial respiratory chain complex I assembly; mitochondrial electron transport, NADH to ubiquinone; blastocyst hatching;
	Sources:Amigo / QuickGO
Orthologs
	4695
	17991
	ENSG00000131495
	ENSMUSG00000014294
	O43678
	Q9CQ75
	NM_001185012; NM_002488
	NM_010885
	NP_001171941; NP_002479
	NP_035015
	Wikidata
View/Edit Human	View/Edit Mouse

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 is a protein that in humans is encoded by the NDUFA2 gene. The NDUFA2 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. Mutations in the NDUFA2 gene are associated with Leigh's syndrome.