NDUFAF7

NDUFAF7
Identifiers
Aliases	NDUFAF7, C2orf56, MidA, PRO1853, NADH:ubiquinone oxidoreductase complex assembly factor 7
External IDs	OMIM: 615898; MGI: 1920944; HomoloGene: 12508; GeneCards: NDUFAF7; OMA:NDUFAF7 - orthologs
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	79,255,481 bp
Gene ontology
Molecular function	enzyme binding; protein binding; methyltransferase activity; transferase activity; protein-arginine omega-N symmetric methyltransferase activity;
Cellular component	mitochondrial matrix; mitochondrion; extracellular space;
Biological process	mitochondrial respiratory chain complex I assembly; ATP metabolic process; methylation; peptidyl-arginine methylation, to symmetrical-dimethyl arginine;
	Sources:Amigo / QuickGO
Orthologs
	55471
	73694
	ENSG00000003509
	ENSMUSG00000024082
	Q7L592
	Q9CWG8
	NM_001083946; NM_018607; NM_144736
	NM_028611; NM_144760
	NP_001077415; NP_653337; NP_001336953; NP_001336954; NP_001336956
	NP_082887
	Wikidata
View/Edit Human	View/Edit Mouse

Protein arginine methyltransferase NDUFAF7, mitochondrial, also known as NADH:ubiquinone oxidoreductase complex assembly factor 7 (NDUFAF7), MidA, C2orf56, or PRO1853, is a protein that in humans is encoded by the NDUFAF7 gene. NDUFAF7 is a methyltransferase mitochondrial assembly enzyme involved in the assembly and stabilization of NADH dehydrogenase (ubiquinone) also known as complex I, which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. Mutations in NDUFAF7 have been associated with pathologic myopia and complex I deficiency.