NDUFB8

NDUFB8
Identifiers
Aliases	NDUFB8, ASHI, CI-ASHI, NADH:ubiquinone oxidoreductase subunit B8, MC1DN32
External IDs	OMIM: 602140; MGI: 1914514; HomoloGene: 3668; GeneCards: NDUFB8; OMA:NDUFB8 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	100,530,000 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	44,543,879 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; lateral nuclear group of thalamus; ; Brodmann area 23; ; Pons; ; Epithelium of choroid plexus; ; middle temporal gyrus; ; Brodmann area 9; ; superior vestibular nucleus; ; right frontal lobe; ; pars compacta;
	Top expressed in
	right kidney; ; digastric muscle; ; sternocleidomastoid muscle; ; triceps brachii muscle; ; thoracic diaphragm; ; temporal muscle; ; intercostal muscle; ; myocardium of ventricle; ; soleus muscle; ; extensor digitorum longus muscle;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	NADH dehydrogenase (ubiquinone) activity; NADH dehydrogenase activity;
Cellular component	integral component of membrane; mitochondrial inner membrane; respirasome; endoplasmic reticulum; membrane; mitochondrion; mitochondrial respiratory chain complex I; mitochondrial matrix;
Biological process	mitochondrial respiratory chain complex I assembly; mitochondrial electron transport, NADH to ubiquinone;
	Sources:Amigo / QuickGO
Orthologs
	4714
	67264
	ENSG00000166136
	ENSMUSG00000025204
	O95169
	Q9D6J5
	NM_005004; NM_001284367; NM_001284368
	NM_026061; NM_001347447
	NP_001271296; NP_001271297; NP_004995
	NP_001334376; NP_080337
	Wikidata
View/Edit Human	View/Edit Mouse

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial is an enzyme that in humans is encoded by the NDUFB8 gene. NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8 is an accessory subunit of the NADH dehydrogenase (ubiquinone) complex, located in the mitochondrial inner membrane. It is also known as Complex I and is the largest of the five complexes of the electron transport chain.