NDUFS7

NDUFS7
Identifiers
Aliases	NDUFS7, CI-20, CI-20KD, MY017, PSST, NADH:ubiquinone oxidoreductase core subunit S7, MC1DN3
External IDs	OMIM: 601825; MGI: 1922656; HomoloGene: 11535; GeneCards: NDUFS7; OMA:NDUFS7 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	1,395,589 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	80,092,628 bp
RNA expression pattern
	Top expressed in
	muscle of thigh; ; apex of heart; ; gastrocnemius muscle; ; mucosa of transverse colon; ; right auricle of heart; ; C1 segment; ; left ventricle; ; right hemisphere of cerebellum; ; left testis; ; right testis;
	Top expressed in
	interventricular septum; ; facial motor nucleus; ; myocardium of ventricle; ; digastric muscle; ; extraocular muscle; ; soleus muscle; ; thoracic diaphragm; ; cardiac muscles; ; right ventricle; ; masseter muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	4 iron, 4 sulfur cluster binding; quinone binding; iron-sulfur cluster binding; metal ion binding; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; protein binding; oxidoreductase activity; NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity; protease binding;
Cellular component	synaptic membrane; soma; mitochondrial matrix; mitochondrion; neuron projection; respirasome; mitochondrial respiratory chain complex I;
Biological process	mitochondrial respiratory chain complex I assembly; mitochondrial electron transport, NADH to ubiquinone; aerobic respiration; electron transport coupled proton transport;
	Sources:Amigo / QuickGO
Orthologs
	374291
	75406
	ENSG00000115286
	ENSMUSG00000020153
	O75251
	Q9DC70
	NM_024407; NM_001363602
	NM_029272; NM_001364694
	NP_077718; NP_001350531
	NP_083548; NP_001351623
	Wikidata
View/Edit Human	View/Edit Mouse

NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial, also knowns as NADH-ubiquinone oxidoreductase 20 kDa subunit, Complex I-20kD (CI-20kD), or PSST subunit is an enzyme that in humans is encoded by the NDUFS7 gene. The NDUFS7 protein is a subunit of NADH dehydrogenase (ubiquinone) also known as Complex I, which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain.