NECAB2

NECAB2
Identifiers
Aliases	NECAB2, EFCBP2, N-terminal EF-hand calcium binding protein 2, stip-2
External IDs	OMIM: 618130; MGI: 2152211; HomoloGene: 62200; GeneCards: NECAB2; OMA:NECAB2 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	84,002,776 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	120,199,379 bp
RNA expression pattern
	Top expressed in
	nucleus accumbens; ; caudate nucleus; ; Amygdala; ; putamen; ; cingulate gyrus; ; anterior cingulate cortex; ; right frontal lobe; ; Brodmann area 9; ; Hypothalamus; ; prefrontal cortex;
	Top expressed in
	habenula; ; olfactory tubercle; ; lateral septal nucleus; ; dentate gyrus of hippocampal formation granule cell; ; medial geniculate nucleus; ; anterior amygdaloid area; ; medial dorsal nucleus; ; subiculum; ; nucleus accumbens; ; globus pallidus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding; protein binding; calcium ion binding; A2A adenosine receptor binding; type 5 metabotropic glutamate receptor binding; identical protein binding;
Cellular component	cytoplasm; plasma membrane; membrane; axon; dendrite; cell projection;
Biological process	positive regulation of adenosine receptor signaling pathway; positive regulation of ERK1 and ERK2 cascade; positive regulation of glutamate receptor signaling pathway; negative regulation of G protein-coupled receptor internalization; positive regulation of protein localization to membrane; regulation of amyloid precursor protein biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	54550
	117148
	ENSG00000103154
	ENSMUSG00000031837
	Q7Z6G3
	Q91ZP9
	NM_019065; NM_001329748; NM_001329749
	NM_054095
	NP_001316677; NP_001316678; NP_061938
	NP_473436
	Wikidata
View/Edit Human	View/Edit Mouse

N-terminal EF-hand calcium-binding protein 2 is a protein that in humans is encoded by the NECAB2 gene.