Neurogenin-2

NEUROG2
Identifiers
Aliases	NEUROG2, Atoh4, Math4A, NGN2, bHLHa8, ngn-2, neurogenin 2
External IDs	OMIM: 606624; MGI: 109619; HomoloGene: 7633; GeneCards: NEUROG2; OMA:NEUROG2 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	112,516,180 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	127,429,280 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; gonad; ; right hemisphere of cerebellum; ; putamen; ; Amygdala; ; caudate nucleus; ; hippocampus proper; ; prefrontal cortex; ; anterior cingulate cortex;
	Top expressed in
	ventricular zone; ; rhombic lip; ; fossa; ; urethra; ; ganglion of neuraxis; ; ganglionic eminence; ; pretectal area; ; neural crest; ; condyle; ; zona limitans intrathalamica;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; E-box binding; protein dimerization activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	multicellular organism development; nervous system development; regulation of transcription, DNA-templated; positive regulation of DNA-binding transcription factor activity; neuron differentiation; cell differentiation; transcription, DNA-templated; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	63973
	11924
	ENSG00000178403
	ENSMUSG00000027967
	Q9H2A3
	P70447
	NM_024019
	NM_009718
	NP_076924
	NP_033848
	Wikidata
View/Edit Human	View/Edit Mouse

Neurogenin-2 is a protein that in humans is encoded by the NEUROG2 gene.

Neurogenin-2 is a member of the neurogenin subfamily of basic helix-loop-helix (bHLH) transcription factor genes that play an important role in neurogenesis.

It has been found to reprogram astrocytes to glutamatergic neurons when expressed.