NFASC

NFASC
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3P3Y, 3P40
Identifiers
Aliases	NFASC, NF, NRCAML, neurofascin, NEDCPMD
External IDs	OMIM: 609145; MGI: 104753; HomoloGene: 24945; GeneCards: NFASC; OMA:NFASC - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	205,022,822 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	132,669,535 bp
RNA expression pattern
	Top expressed in
	inferior olivary nucleus; ; lateral nuclear group of thalamus; ; external globus pallidus; ; corpus callosum; ; dorsal motor nucleus of vagus nerve; ; inferior ganglion of vagus nerve; ; glomerulus; ; metanephric glomerulus; ; pars reticulata; ; pars compacta;
	Top expressed in
	neural layer of retina; ; visual cortex; ; primary visual cortex; ; central gray substance of midbrain; ; cerebellar cortex; ; superior cervical ganglion; ; superior frontal gyrus; ; anterior horn of spinal cord; ; pontine nuclei; ; lumbar subsegment of spinal cord;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein domain specific binding; protein binding; protein binding involved in heterotypic cell-cell adhesion;
Cellular component	integral component of membrane; membrane; focal adhesion; myelin sheath; plasma membrane; Schwann cell microvillus; intracellular anatomical structure; axon; paranodal junction; axon initial segment; paranode region of axon; extracellular exosome; node of Ranvier; ficolin-1-rich granule membrane; dendrite; integral component of plasma membrane;
Biological process	clustering of voltage-gated sodium channels; peripheral nervous system development; transmission of nerve impulse; heterotypic cell-cell adhesion; synapse organization; protein localization to paranode region of axon; cell adhesion; paranodal junction assembly; myelination; protein localization to juxtaparanode region of axon; axon guidance; neutrophil degranulation; protein localization to plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	23114
	269116
	ENSG00000163531
	ENSMUSG00000026442
	O94856
	Q810U3
NM_001005387; NM_001005388; NM_001005389; NM_001160331; NM_001160332;
	NM_001160333; NM_015090; NM_001365986; NM_001378330; NM_001378331; NM_001378329
	NM_001160316; NM_001160317; NM_001160318; NM_182716
NP_001005388; NP_001005389; NP_001153803; NP_001153804; NP_001153805;
	NP_055905; NP_001352915; NP_001365259; NP_001365260; NP_001365258
	NP_001153788; NP_001153789; NP_001153790; NP_874385
	Wikidata
View/Edit Human	View/Edit Mouse

Neurofascin is a protein that in humans is encoded by the NFASC gene.