NFATC1

NFATC1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1A66, 1NFA
Identifiers
Aliases	NFATC1, NF-ATC, NFAT2, NFATc, NF-ATc1.2, nuclear factor of activated T-cells 1, nuclear factor of activated T cells 1
External IDs	OMIM: 600489; MGI: 102469; HomoloGene: 32336; GeneCards: NFATC1; OMA:NFATC1 - orthologs
Gene location (Human)
Chr.	Chromosome 18 (human)
End	79,529,325 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	80,756,286 bp
RNA expression pattern
	Top expressed in
	oocyte; ; muscle of thigh; ; secondary oocyte; ; Skeletal muscle tissue of rectus abdominis; ; triceps brachii muscle; ; gastrocnemius muscle; ; Skeletal muscle tissue of biceps brachii; ; sural nerve; ; glutes; ; vastus lateralis muscle;
	Top expressed in
	granulocyte; ; mesenteric lymph nodes; ; endocardial cushion; ; triceps brachii muscle; ; muscle of thigh; ; olfactory epithelium; ; knee joint; ; temporal muscle; ; blood; ; ankle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity; mitogen-activated protein kinase p38 binding; FK506 binding; DNA-binding transcription activator activity, RNA polymerase II-specific; protein binding; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; DNA-binding transcription factor activity, RNA polymerase II-specific; chromatin binding; transcription factor binding;
Cellular component	cytoplasm; cytosol; nucleus; nucleoplasm; nuclear body; transcription regulator complex;
Biological process	intracellular signal transduction; regulation of transcription, DNA-templated; calcineurin-NFAT signaling cascade; transcription by RNA polymerase II; transcription, DNA-templated; positive regulation of transcription, DNA-templated; Fc-epsilon receptor signaling pathway; positive regulation of transcription by RNA polymerase II; Wnt signaling pathway, calcium modulating pathway; negative regulation of Wnt signaling pathway; negative regulation of vascular associated smooth muscle cell differentiation; cytokine production; aortic valve morphogenesis; pulmonary valve morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	4772
	18018
	ENSG00000131196
	ENSMUSG00000033016
	O95644
	O88942
NM_172390; NM_001278669; NM_001278670; NM_001278672; NM_001278673;
	NM_001278675; NM_006162; NM_172387; NM_172388; NM_172389
NM_001164109; NM_001164110; NM_001164111; NM_001164112; NM_016791;
	NM_198429
NP_001265598; NP_001265599; NP_001265601; NP_001265602; NP_001265604;
	NP_006153; NP_765975; NP_765976; NP_765977; NP_765978
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Nuclear factor of activated T-cells, cytoplasmic 1 is a protein that in humans is encoded by the NFATC1 gene.