NFATC2

NFATC2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1A02, 1OWR, 1P7H, 1PZU, 2AS5, 2O93, 3QRF
Identifiers
Aliases	NFATC2, NFAT1, NFATP, nuclear factor of activated T-cells 2, nuclear factor of activated T cells 2
External IDs	OMIM: 600490; MGI: 102463; HomoloGene: 7861; GeneCards: NFATC2; OMA:NFATC2 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	51,562,831 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	168,443,577 bp
RNA expression pattern
	Top expressed in
	vena cava; ; synovial joint; ; synovial membrane; ; nipple; ; buccal mucosa cell; ; pylorus; ; tendon of biceps brachii; ; cartilage tissue; ; saphenous vein; ; skin of arm;
	Top expressed in
	lumbar subsegment of spinal cord; ; motor neuron; ; substantia nigra; ; ankle; ; condyle; ; facial motor nucleus; ; stroma of bone marrow; ; soleus muscle; ; mesenteric lymph nodes; ; Epithelium of choroid plexus;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; transcription factor binding; chromatin binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; protein binding; transcription cis-regulatory region binding; phosphatase binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; transcription regulator complex; nucleoplasm; nucleus; cytosol; ribonucleoprotein complex;
Biological process	B cell receptor signaling pathway; regulation of transcription, DNA-templated; cytokine production; calcineurin-NFAT signaling cascade; negative regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; myotube cell development; transcription, DNA-templated; cellular response to DNA damage stimulus; positive regulation of transcription, DNA-templated; Fc-epsilon receptor signaling pathway; positive regulation of myoblast fusion; positive regulation of gene expression; positive regulation of B cell proliferation; cell migration; positive regulation of transcription by RNA polymerase II; regulation of regulatory T cell differentiation; negative regulation of vascular associated smooth muscle cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	4773
	18019
	ENSG00000101096
	ENSMUSG00000027544
	Q13469
	Q60591
NM_001136021; NM_001258292; NM_001258294; NM_001258295; NM_001258296;
	NM_001258297; NM_012340; NM_173091
NM_001037177; NM_001037178; NM_001136073; NM_001291168; NM_001291169;
	NM_001291170; NM_001291171; NM_001291172; NM_001291173; NM_001291174; NM_001291175; NM_001291176; NM_001291177; NM_001291178; NM_001291179; NM_010899
NP_001129493; NP_001245221; NP_001245223; NP_001245224; NP_001245225;
	NP_001245226; NP_036472; NP_775114
NP_001032254; NP_001032255; NP_001129545; NP_001278097; NP_001278098;
	NP_001278099; NP_001278100; NP_001278101; NP_001278102; NP_001278103; NP_001278104; NP_001278105; NP_001278106; NP_001278107; NP_001278108; NP_035029
	Wikidata
View/Edit Human	View/Edit Mouse

Nuclear factor of activated T-cells, cytoplasmic 2 is a protein that in humans is encoded by the NFATC2 gene.