NFKBID

NFKBID
Identifiers
Aliases	NFKBID, IkappaBNS, TA-NFKBH, NFKB inhibitor delta, IkBNS
External IDs	MGI: 3041243; HomoloGene: 13101; GeneCards: NFKBID; OMA:NFKBID - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	35,902,303 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	30,128,171 bp
RNA expression pattern
	Top expressed in
	bone marrow cells; ; granulocyte; ; sural nerve; ; monocyte; ; blood; ; appendix; ; mucosa of ileum; ; spleen; ; upper lobe of left lung; ; left lobe of thyroid gland;
	Top expressed in
	granulocyte; ; mesenteric lymph nodes; ; thymus; ; spleen; ; bone marrow; ; stroma of bone marrow; ; blood; ; embryo; ; embryo; ; subcutaneous adipose tissue;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; transcription coregulator activity; NF-kappaB binding;
Cellular component	nucleus;
Biological process	regulation of transcription by RNA polymerase II; negative regulation of T cell differentiation in thymus; positive regulation of thymocyte apoptotic process; inflammatory response; negative regulation of NF-kappaB transcription factor activity; negative regulation of I-kappaB kinase/NF-kappaB signaling; T cell receptor signaling pathway; positive regulation of T-helper 17 cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	84807
	243910
	ENSG00000167604
	ENSMUSG00000036931
	Q8NI38
	Q2TB02
	NM_139239; NM_001321831; NM_001365705; NM_001365706; NM_032721
	NM_172142; NM_001360906; NM_001360907
	NP_001308760; NP_640332; NP_001352634; NP_001352635; NP_116110
	NP_742154; NP_001347835; NP_001347836
	Wikidata
View/Edit Human	View/Edit Mouse

Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta also known as IκBNS is a protein in humans that is encoded by the NFKBID gene.

IκBNS is a member of the atypical inhibitors of NF-κB (also called the nuclear IκBs). NF-κB is a transcription factor, which regulates the expression of its target genes, depending on intracellular and extracellular signals. As NFKBID influences the impact of NF-κB on several genes, it is involved in cellular responses to stimuli such as stress and bacterial or viral antigens.