Nidogen-1

NID1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1NDX
Identifiers
Aliases	NID1, NID, nidogen 1, entactin
External IDs	OMIM: 131390; MGI: 97342; HomoloGene: 1878; GeneCards: NID1; OMA:NID1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	236,065,109 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	13,686,854 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; gastric mucosa; ; lower lobe of lung; ; left uterine tube; ; right lung; ; pericardium; ; pylorus; ; canal of the cervix; ; placenta; ; subcutaneous adipose tissue;
	Top expressed in
	endothelial cell of lymphatic vessel; ; epithelium of lens; ; epididymis; ; external carotid artery; ; internal carotid artery; ; efferent ductule; ; left lung lobe; ; trophoblast cell; ; Gonadal ridge; ; dermis;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	laminin-1 binding; calcium ion binding; laminin binding; collagen binding; extracellular matrix binding; proteoglycan binding; extracellular matrix structural constituent;
Cellular component	extracellular matrix; extracellular region; basement membrane; extracellular exosome; cell periphery; extracellular space; collagen-containing extracellular matrix;
Biological process	cell-matrix adhesion; extracellular matrix disassembly; extracellular matrix organization; cell adhesion; glomerular basement membrane development; basement membrane organization; positive regulation of cell-substrate adhesion;
	Sources:Amigo / QuickGO
Orthologs
	4811
	18073
	ENSG00000116962
	ENSMUSG00000005397
	P14543
	P10493
	NM_002508
	NM_010917
	NP_002499
	NP_035047
	Wikidata
View/Edit Human	View/Edit Mouse

Nidogen-1 (NID-1), formerly known as entactin, is a protein that in humans is encoded by the NID1 gene. Both nidogen-1 and nidogen-2 are essential components of the basement membrane alongside other components such as type IV collagen, proteoglycans (heparan sulfate and glycosaminoglycans), laminin and fibronectin.